Pegaquest

PHARMACOLOGICAL ACTION PEGAQUEST® contains the active ingredients, moxidectin, a second generation macrocyclic lactone as well as praziquantel. Praziquantel is a broad spectrum cestocide and is an effective treatment against tapeworm in horses. The paste formulation is banana flavoured, palatable and effective against the most important roundworm species and bots in horses. It is used for the treatment and control of roundworms (including arterial larval stages of Strongylus vulgaris), bots, adult and late encysted small strongyles, tapeworms and Habronema spp.

PEGAQUEST® is effective against the following parasites: Large strongyles: Strongylus edentatus (adults and immatures), Strongylus vulgaris (adults, immatures and arterial larval stages), Strongylus equinus and Triodontophorus spp. Small strongyles: including Cyathostomum spp., Cylicostephanus spp., Cylicocyclus spp., Cylicodontophorus spp., Gyalocephalus spp. and the encysted stages of small strongyles Ascarids: Parascaris equorum (adults and immatures) Pinworms: Oxyuris equi (adults and immatures) Hairworms: Trichostrongylus axei (adults) Threadworms: Strongyloides westeri (adults) Largemouthed stomach worms: Habronema spp. (gastric and cutaneous [summer sore] forms) and Draschia spp. Lung worms: Dictyocaulus arnfieldi (adults and immatures) Tapeworms: Paranoplocephala spp. and Anoplocephala spp. Stomach bots: Immature Gasterophilus intestinalis and Gasterophilus nasalis Cutaneous onchocerciasis: Onchocerca spp. (microfilaria)

WARNINGS • Do not use on animals intended for human consumption. • Do not administer the full syringe to horses weighing less than 400 kg. • Extremely toxic to aquatic species. Do not contaminate dams, rivers, streams or other waterways with the product or used container. • Keep out of reach of children, uninformed persons and animals. • Although this product has been extensively tested under a large variety of conditions, failure thereof may ensue as a result of a wide range of reasons. If this is suspected, seek veterinary advice and notify the registration holder.

PRECAUTIONS • Accurately determine the mass of the horse to be treated and adjust the syringe to the correct dose for the horse. • Poisonous to humans if swallowed. • Wash hands after use. • Will irritate eyes and skin.

DOSAGE AND DIRECTIONS FOR USE Use only as directed. Accurately determine the mass of the horse to be treated. Turn the ring on the plunger to the correct dosage setting in accordance with the horse’s weight. When used as directed

PEGAQUEST® is safe for use in foals over 4 weeks of age and in all breeding stock, including stallions and pregnant mares. The PEGAQUEST® syringe is graduated in intervals of 100 kg body mass. The contents of this syringe will treat a horse of 600 kg. Dosage: PEGAQUEST® is orally administered at a dose rate of 0,4 mg/kg moxidectin and 2,5 mg praziquantel per kg body mass.

ADMINISTRATION • Ensure that the horse’s mouth is free of food before administration. • The body mass of the horse should be determined accurately to facilitate correct dosing of the paste. • Insert the syringe into the side of the horse’s mouth in the gap between the front and back teeth and deliver the paste onto the back of the tongue. • Raise the horse’s head for a few seconds immediately after dosing to ensure that the full dose has been swallowed. Parasite control programme: Regular treatment will reduce the risk of disease due to small and large strongyles such as colic and verminous arteritis. Reinfection of horses with worms is common. Treatment must be routinely repeated to ensure effective control. The long-term activity of PEGAQUEST® against worms, including encysted small strongyles, is very useful in reducing the required dosing frequency in strategic parasite control programmes. Retreatment intervals can be safely extended up to 13 weeks. Consult your veterinarian for advice on the appropriate programme to meet your specific needs.

PRESENTATION: Calibrated syringe containing 12,2 g nett content enclosed in a unit carton together with a package insert.

STORAGE INSTRUCTIONS: Store at or below 25 ºC (room temperature) in a cool, dark place. Protect from direct sunlight. Reg. No. G4162 Act 36/1947 DOSAGE FORM Oral Paste

COMPOSITION Moxidectin 20 mg/mℓ (2 % m/v), Praziquantel 125 mg/mℓ (12,5 % m/v)

INDICATIONS Broad spectrum dewormer for horses.